The Pelicans outscored the Nuggets in every quarter on their way to a 122-107 win in New Orleans.
Jahlil Okafor scored 26 points and Brandon Ingram added 25 for the Pelicans, who improved to 1-4 on the season.
Frank Jackson scored 21 off the bench and Jrue Holiday pitched in with 19 points in the victory.
Michael Porter Jr. led seven Denver players in double-figures with 15 points off the pine.
Jamal Murray and Jerami Grant netted 14 apiece for the Nuggets, who dropped to 3-2.
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